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Primary analysis showed trials reporting surrogate endpoints to have larger treatment effects (odds ratio 0.51, 95% confidence interval 0.42 to 0.60) than trials reporting patient relevant outcomes (0.76, 0.70 to 0.82), with an unadjusted ratio of odds ratios of 1.47 (1.07 to 2.01) and adjusted ratio of odds ratios of 1.46 (1.05 to 2.04).
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Although, and maybe I'm in the minority, I don't particularly care for Nightfall strikes. At its worst, contemporary British culture attributes adult motives to children's behaviour. A funny thing happens when a manufacturer uses the same basic chassis and drivetrain for a couple of decades: at some point, every succeeding generation becomes a refinement and modification of the last.
21 with on time airport but low score in health and safetyMinneapolis gets high marks for gardens and citywide Internet accessTo assess which places help you make the most of your precious hours, we sorted through reams of data on dozens of large American cities, ranked each on various criteria in five categories (see below) on a scale of 1 to 5, and added up those categories to get an overall score.Category 1: Getting around Includes average commute, walkability, traffic congestion, airport on time performance.Category 2: Health and safety Includes average wait to get a doctor's appointment, physicians per capita, response times of emergency medical services.Category 3: Information and technology Includes broadband and wireless availability, bookstores and libraries per capita, helpful resources such as 311 hotlines.Category 4: Green time savers Includes recycling access and cost, number of farmers' markets and community gardens, bike friendliness.Category 5: Lifestyle Includes number of personal trainers and organizers, restaurants offering takeout per capita, miscellaneous time saving services.1.
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